Leupeptin Hemisulfate( Acetyl-L-leucyl-L-leucyl-L-argininal )

Catalog No. M10170 CAS No. 103476-89-7

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HNMR

HPLC

MSDS

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Product Name

Leupeptin Hemisulfate
Note

Research use only, not for human use.
Brief Description

Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases.
Description

Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases.
In Vitro

——
In Vivo

Animal Model:C57BL/6NCrl male mice (6-8 weeks old, 20-25 g) Dosage:0, 9, 18, 36 mg/kg Administration:Intraperitoneal injection; single Result:Promoted the accumulation of LC3b-II in mouse liver.
Synonyms

Acetyl-L-leucyl-L-leucyl-L-argininal
Pathway

Proteasome/Ubiquitin
Target

Cysteine Protease
Recptor

Cysteine protease| Serine Protease
Research Area

Infection
Indication

——

CAS Number

103476-89-7
Formula Weight

475.59
Molecular Formula

C20H38N6O4·1/2H2SO4
Purity

>98% (HPLC)
Solubility

Ethanol: 95 mg/mL (199.75 mM); Water: 95 mg/mL (199.75 mM); DMSO: 95 mg/mL warmed (199.75 mM)
SMILES

CC(C)C[C@@H](C(N)=O)N(C([C@H](CC(C)C)NC(C)=O)=O)[C@H](C=O)CCCNC(N)=N.CC(C)C[C@@H](C(N)=O)N(C([C@H](CC(C)C)NC(C)=O)=O)[C@H](C=O)CCCNC(N)=N.O=S(O)(O)=O
Chemical Name

(S)-2-acetamido-N-((S)-1-amino-4-methyl-1-oxopentan-2-yl)-N-((S)-5-guanidino-1-oxopentan-2-yl)-4-methylpentanamide hemisulfate

1. Aoyagi T, et al. J Antibiot (Tokyo). 1969, 22(11), 558-568.

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